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Her short story collections are Self-Help, Like Life, and the New York Times bestseller Birds of America. She has contributed to The Paris Review. Her first story to appear in The New Yorker, "You're Ugly, Too," was later included in The Best American Short Stories of the Century, edited by John Updike. Another story, "People Like That Are the Only People Here," also published in The New Yorker, was reprinted in the 1998 edition of the annual collection The Best American Short Stories; the tale of a young child falling sick, the piece was loosely paterned on events in Moore's own life. The story was also included in the 2005 anthology Children Playing Before a Statue of Hercules, edited by David Sedaris.
Moore's Collected Stories was published by Faber in the UK in May 2008. It included selections from each of her previously published collections, excerpts from her novel Anagrams, and three previously uncollected stories first published in The New Yorker.
Moore's novels are Anagrams (1986), Who Will Run the Frog Hospital? (1994), and A Gate at the Stairs (2009). Who Will Run the Frog Hospital is the story of a woman vacationing with her husband who recalls an intense friendship from her adolescence. A Gate at the Stairs takes place just after the September 11 attack and is about a twenty-year-old Midwestern woman's coming of age.
Moore has written a children's book entitled The Forgotten Helper, about an elf whom Santa mistakenly leaves behind at the home of the worst child on his "good" list. The elf must help the child be good for the coming year so Santa will return next Christmas.
Moore writes frequently about popular culture for The New York Review of Books.