John Lennon, known for being a member of the Beatles and also for his peaceful views and his books, In His Own Write and A Spaniard in the Works, was given a copy of Alas, Babylon by journalist Larry Kane in 1965. Lennon spent all night reading the book, fueling his anti-war fervor and causing him to envision the people of the world attempting to crawl their way back from the horrors of a nuclear catastrophe.
In the foreword of the 2005 edition of Alas, Babylon, David Brin notes that the book was instrumental in shaping his views on nuclear war and had an effect on his own book, The Postman.
In the acknowledgements section at the beginning of his 2009 post-apocalyptic novel One Second After, William R. Forstchen credits Alas, Babylon as an influence in writing his novel about the small town of Black Mountain, North Carolina. The novel is set in a time after numerous electromagnetic pulse strikes around the world cut off all sources of electricity to the town and depicts the ensuing aftermath of sociological breakdown.
The story of purported time traveler John Titor has similarities to Alas, Babylon, most specifically, the Florida setting and the post-apocalyptic culture described in the novel. This similarity has been specifically addressed by detractors who doubted the authenticity of Titor's claims.