California punk rock band Lagwagon's song "Owen Meaney" from their 1998 album Let's Talk About Feelings is based on the book.
The band Jimmy Eat World based the song "Goodbye Sky Harbor" from their 1999 album Clarity on the book.
In the movie Milk Money, the school is named Owen Meany Jr. High School.
Former Los Angeles Lakers coach Phil Jackson has passed out this book to his team in the past as part of his ritual of assigning readings to players.[18] Book is featured on the TV show "Tacoma FD".
